While Goji cannot improve the shelf lives of important medical supplies such as blood and plasma, we can ensure their quality and improve the ability of healthcare professionals to work with frozen stores.
We are currently applying our AVED technology to the following healthcare applications:
- plasma thawing and red blood cell (RBC) heating
- operating room (OR) materials thawing
- freeze drying of blood and stem cells
Febris - Rapid Thawing and Heating of Biological Materials
The Febris device enables rapid, easy and safe thawing and heating of human plasma-based fibrin sealant and other frozen biological materials. A compact self-contained device, Febris enables on demand thawing of frozen biomaterials during surgery.
Febris can thaw and heat biological materials in a fraction of the time required by conventional heating methods such as water baths. Febris can thaw a 10mL fibrin sealant unit within just one minute. Fibrin sealant units thawed by Febris demonstrate equivalent clotting times to units thawed in water baths.
Febris is safe and simple to operate, and does not involved tedious maintenance procedures required for draining and cleaning conventional thawing chambers. Capable of accommodating various biomaterials unit sizes, Febris is a scalable device that can heat multiple fibrin units simultaneously, and can also be configured to support the thawing and heating of additional frozen biomaterials.
- Unrivaled ease of use
- On demand thawing/heating from -80 degrees Celsius to 37 degrees Celsius in under 60 seconds
- Versatile accommodation of various fibrin sealant unit configurations and sizes
- Easy configuration for additional biomaterials
- Dated log of thawed units for inventory tracking
For many years people have been trying to introduce RF volumetric heating to freeze drying (lyophilization) with no success. The main reasons behind this failure are the lack of uniformity of the freeze-drying process and corona discharge that causes severe damage to the lyophilized product. Our new volumetric heating system offers a closed feedback loop RF/electromagnetic energy-delivery system with a homogeneous heating profile over large volumetric samples, supported by our unique sensor for corona discharge detection.
Speed: Comparative studies using our prototype lyophilizer show a significant reduction in cycle time with no additional damage to the tested material. Energy delivery during lyophilization is free from conventional limitations of conduction and convection. Studies showed that process time was reduced to 10% of the standard cycle, and current simulations are targeting a reduction to 5% of the cycle time.
Homogeneity: Our system is designed to continuously measure energy delivery and absorption by the sample. Heating is performed in a homogeneous manner to the evaporation front, generating a high-quality product.
Flexibility: The ability to deliver energy without depending on shelf temperature allows for more flexibility in process design. Our system performs lyophilization at a low temperature (but in a short time) to reduce damage of delicate substances. This flexibility enables a variety of new potential freeze-drying applications including developing a continuous process, and designing new containers with a selective energy-delivery algorithm where only one compartment will be lyophilized and the other will be used for diluents. By reducing process time and relaxing the physical limitations of conventional lyophilization, improved product quality can be achieved.
Download the Febris brochure here